Involvement of filamentous actin in setting the threshold for degranulation in mast cells.

@article{Tolarov2004InvolvementOF,
  title={Involvement of filamentous actin in setting the threshold for degranulation in mast cells.},
  author={Helena Tolarov{\'a} and Petr Heneberg and Petr Dr{\'a}ber},
  journal={European journal of immunology},
  year={2004},
  volume={34 6},
  pages={
          1627-36
        }
}
Previous studies using cytochalasins and latrunculin B, inhibitors of actin polymerization, showed that filamentous (F)-actin had a negative regulatory role in Fc epsilon receptor I (Fc epsilon RI) signaling. How F-actin is involved in regulating the activation of mast cells is unknown. In this study we investigated the role of F-actin in mast cell activation induced by aggregation of the glycosylphosphatidylinositol (GPI)-anchored proteins Thy-1 and TEC-21, and compared it to activation via Fc… CONTINUE READING
BETA

Citations

Publications citing this paper.
SHOWING 1-10 OF 17 CITATIONS, ESTIMATED 33% COVERAGE

52 Citations

051015'06'09'12'15'18
Citations per Year
Semantic Scholar estimates that this publication has 52 citations based on the available data.

See our FAQ for additional information.

Similar Papers

Loading similar papers…