Involvement of equine chorionic gonadotropin (eCG) carbohydrate side chains in its bioactivity; lessons from recombinant hormone expressed in insect cells.

@article{Legardinier2005InvolvementOE,
  title={Involvement of equine chorionic gonadotropin (eCG) carbohydrate side chains in its bioactivity; lessons from recombinant hormone expressed in insect cells.},
  author={S{\'e}bastien Legardinier and Claire Cahoreau and Dani{\`e}le Klett and Yves Combarnous},
  journal={Reproduction, nutrition, development},
  year={2005},
  volume={45 3},
  pages={255-9}
}
Natural eCG consists of as much as 45% carbohydrate side chains. The present paper deals with the analysis of the roles of the N- and O-linked saccharides of this hormone in the different steps of its activity and its possible replacement by recombinant eCG expressed in baculovirus-insect cell systems.