Involvement of epidermal growth factor in inducing adiposity of age female mice.

@article{Adachi1995InvolvementOE,
  title={Involvement of epidermal growth factor in inducing adiposity of age female mice.},
  author={Hideo Adachi and Hirohisa Kurachi and Hideaki Homma and Kazushige Adachi and Taihei Imai and Masahiro Sakata and Yuji Matsuzawa and Akira Miyake},
  journal={The Journal of endocrinology},
  year={1995},
  volume={146 3},
  pages={381-93}
}
Aged mice exhibit an increase in their body weight (BW), which is associated with fat deposit increase. Epidermal growth factor (EGF) concentration in the submandibular gland also increases with aging. We examined the effects of elevated EGF on the adiposity of aged female mice. Studies were started in two groups of animals consisting of sham-operated (n = 10) and sialoadenectomized (n = 10, Sx; surgical removal of the submandibular glands) mice at 8 weeks of age. Body weight gain and food… CONTINUE READING

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