Involvement of electrostatic phenomena in phospholamban-induced stimulation of Ca uptake into cardiac sarcoplasmic reticulum.

@article{Chiesi1989InvolvementOE,
  title={Involvement of electrostatic phenomena in phospholamban-induced stimulation of Ca uptake into cardiac sarcoplasmic reticulum.},
  author={Michele Chiesi and R Schwaller},
  journal={FEBS letters},
  year={1989},
  volume={244 1},
  pages={241-4}
}
The activity of the Ca-pumping ATPase of cardiac sarcoplasmic reticulum (SR) is controlled by the phosphorylation of the intrinsic regulatory protein phospholamban (PLB), which affects both the apparent Km(Ca) and the Vmax of the transport process. We have investigated the correlation between phosphorylation of PLB and the surface potential of the SR… CONTINUE READING