Involvement of dopamine D1/D2 receptors on harmane-induced amnesia in the step-down passive avoidance test.

@article{Nasehi2010InvolvementOD,
  title={Involvement of dopamine D1/D2 receptors on harmane-induced amnesia in the step-down passive avoidance test.},
  author={Mohammad Mahdi Nasehi and Morteza Piri and Maryam Nouri and Davood Farzin and Touraj Nayer-Nouri and Mohammad Reza Zarrindast},
  journal={European journal of pharmacology},
  year={2010},
  volume={634 1-3},
  pages={77-83}
}
Ingestion of harmane and other alkaloids derived from plant Peganum harmala has been shown to elicit profound behavioural and toxic effects in humans, including hallucinations, excitation, feelings of elation, and euphoria. These alkaloids in the high doses can cause a toxic syndrome characterized by tremors and convulsions. Harmane has also been shown to act on a variety of receptor systems in the mammalian brain, including those for serotonin, dopamine and benzodiazepines. In animals, it has… CONTINUE READING
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