Involvement of dendritic cells in the pathogenesis of inflammatory bowel disease.

@article{Len2006InvolvementOD,
  title={Involvement of dendritic cells in the pathogenesis of inflammatory bowel disease.},
  author={Francisco de Paula P{\'e}rez Le{\'o}n and Lesley E. Smythies and Philip D. Coleridge Smith and Brian Lee Kelsall},
  journal={Advances in experimental medicine and biology},
  year={2006},
  volume={579},
  pages={117-32}
}
In conclusion, during inflammation, DCs are likely activated by inflammatory signals and induced to migrate to T cell zones of organized lymphoid tissues where the cells induce T cell responses. In addition to their established role in T cell priming and the induction of tolerance, DCs may act to enhance (or possibly suppress) T cell responses at sites of mucosal inflammation. Determining the importance of DCs in this regard, as well as establishing a potential role for DCs in continuous… CONTINUE READING

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