Involvement of dachshund and Distal-less in distal pattern formation of the cricket leg during regeneration

@inproceedings{Ishimaru2015InvolvementOD,
  title={Involvement of dachshund and Distal-less in distal pattern formation of the cricket leg during regeneration},
  author={Yoshiyasu Ishimaru and Taro Nakamura and Tetsuya Bando and Yuji Matsuoka and Hideyo Ohuchi and Sumihare Noji and Taro Mito},
  booktitle={Scientific reports},
  year={2015}
}
Cricket nymphs have the remarkable ability to regenerate a functional leg following amputation, indicating that the regenerating blastemal cells contain information for leg morphology. However, the molecular mechanisms that underlie regeneration of leg patterns remain poorly understood. Here, we analyzed phenotypes of the tibia and tarsus (three tarsomeres) obtained by knockdown with regeneration-dependent RNA interference (rdRNAi) against Gryllus dachshund (Gb'dac) and Distal-less (Gb'Dll). We… CONTINUE READING

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Here , we analyzed phenotypes of the tibia and tarsus ( three tarsomeres ) obtained by knockdown with regeneration - dependent RNA interference ( rdRNAi ) against Gryllus dachshund ( Gb'dac ) and Distal - less ( Gb'Dll ) .
These results indicate that Gb'Dll expression is indispensable for formation of the tarsus , while Gb'dac expression is necessary for elongation of the tibia and formation of the most proximal tarsomere .
These results indicate that Gb'Dll expression is indispensable for formation of the tarsus , while Gb'dac expression is necessary for elongation of the tibia and formation of the most proximal tarsomere .
Here , we analyzed phenotypes of the tibia and tarsus ( three tarsomeres ) obtained by knockdown with regeneration - dependent RNA interference ( rdRNAi ) against Gryllus dachshund ( Gb'dac ) and Distal - less ( Gb'Dll ) .
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