Involvement of chemokines and Th1 cytokines in the pathogenesis of mucocutaneous lesions of Behçet's disease.

@article{Ahmed2004InvolvementOC,
  title={Involvement of chemokines and Th1 cytokines in the pathogenesis of mucocutaneous lesions of Behçet's disease.},
  author={Malika Ben Ahmed and Habib Houman and Mohamed Sahbi Miled and Koussay Dellagi and Hechmi Louzir},
  journal={Arthritis and rheumatism},
  year={2004},
  volume={50 7},
  pages={2291-5}
}
OBJECTIVE To investigate a possible pathogenic role of cytokines in Behçet's disease (BD) by focusing on the analysis of cytokine gene expression within mucocutaneous BD lesions. METHODS The study group comprised 20 patients with active BD. In this group, a set of chemokines as well as Th1 and Th2 cytokines in biopsy specimens obtained from oral and genital ulcers, pseudofolliculitis lesions, and lesions at the site of pathergy testing were studied using real-time quantitative reverse… CONTINUE READING