Involvement of carrier-mediated transport system in uptake of tetrodotoxin into liver tissue slices of puffer fish Takifugu rubripes.

Abstract

Although puffer fish contain tetrodotoxin (TTX) at a high concentration mainly in liver, the underlying mechanism remains to be elucidated. In the present study, uptake of TTX into the liver tissue slices of puffer fish Takifugu rubripes was investigated by in vitro incubation experiment. When T. rubripes liver slices were incubated with 0-2000microM TTX at… (More)

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@article{Matsumoto2007InvolvementOC, title={Involvement of carrier-mediated transport system in uptake of tetrodotoxin into liver tissue slices of puffer fish Takifugu rubripes.}, author={Takuya Matsumoto and Yuji Nagashima and Hiroyuki Kusuhara and Yuichi Sugiyama and Shoichiro Ishizaki and Kuniyoshi Shimakura and Kazuo Shiomi}, journal={Toxicon : official journal of the International Society on Toxinology}, year={2007}, volume={50 2}, pages={173-9} }