Involvement of capsaicin-sensitive sensory nerves in cardioprotection of rutaecarpine in rats.

@article{Hu2003InvolvementOC,
  title={Involvement of capsaicin-sensitive sensory nerves in cardioprotection of rutaecarpine in rats.},
  author={Chang-ping Hu and Nian-sheng Li and Liang Xiao and Han-wu Deng and Yuanjian Li},
  journal={Regulatory peptides},
  year={2003},
  volume={114 1},
  pages={45-9}
}
In the present study, we examined whether rutaecarpine protects against myocardial ischemia-reperfusion injury in rats and whether the protective effects of rutaecarpine are related to activation of capsaicin-sensitive sensory nerves. Rats were pretreated with rutaecarpine 10 min before the experiment, and then the left main coronary artery of rat hearts was subjected to 60-min occlusion followed by 3-h reperfusion. The infarct size, serum concentration of creatine kinase, and CGRP… CONTINUE READING

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