Involvement of cannabinoid CB1 receptors in the antinociceptive effect of dipyrone


Cannabinoid CB1 receptors have been implicated in the antinociceptive effect of paracetamol. In the current study, we examined whether blockade of CB1 receptors prevent the analgesic activity of dipyrone, in a similar way to paracetamol. Hot-plate and tail-flick tests were used to assess the antinociceptive activity in mice. Dipyrone and WIN 55,212-2, a… (More)
DOI: 10.1007/s00702-013-1052-7


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