Involvement of calcium-activated potassium channels in the regulation of DNA synthesis in cultured Müller glial cells.

@article{Kodal2000InvolvementOC,
  title={Involvement of calcium-activated potassium channels in the regulation of DNA synthesis in cultured M{\"u}ller glial cells.},
  author={Hannes Kodal and Michael Weick and Vanessa Moll and Bernd Biedermann and Andreas Reichenbach and Andreas Bringmann},
  journal={Investigative ophthalmology & visual science},
  year={2000},
  volume={41 13},
  pages={4262-7}
}
PURPOSE To determine the involvement of Ca(2+)-activated K(+) channels of big conductance (BK) and of Ca(2+) channels in the regulation of DNA synthesis in cultured guinea pig Müller cells. DNA synthesis was stimulated by elevated extracellular potassium, by serum, or by epidermal growth factor. METHODS Dissociated retinas from guinea pigs were cultured for 8 days. Just before confluence was achieved, the cultures were treated with the test substances in serum-free or serum-containing media… CONTINUE READING