Involvement of autophagy upregulation in 3,4-methylenedioxymethamphetamine ('ecstasy')-induced serotonergic neurotoxicity.

Abstract

It has been suggested that autophagy plays pathogenetic roles in cerebral ischemia, brain trauma, and neurodegenerative disorders. 3,4-Methylenedioxymethamphetamine (MDMA or ecstasy) is an illicit drug that causes long-term serotonergic neurotoxicity in the brain. Apoptosis and necrosis have been implicated in MDMA-induced neurotoxicity, but the role of… (More)
DOI: 10.1016/j.neuro.2015.11.009

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@article{Li2016InvolvementOA, title={Involvement of autophagy upregulation in 3,4-methylenedioxymethamphetamine ('ecstasy')-induced serotonergic neurotoxicity.}, author={I-Hsun Li and Kuo-Hsing Ma and Tzu-Jen Kao and Yang-Yi Lin and Shao-Ju Weng and Ting-Yin Yen and Lih Chi Chen and Yuahn-Sieh Huang}, journal={Neurotoxicology}, year={2016}, volume={52}, pages={114-26} }