Involvement of apoptosis in the rat germ cell degeneration induced by nitrobenzene

Abstract

Nitrobenezene (NB) produces germ cell degeneration, especially of spermatocytes in rats. To examine the possible involvement of apoptosis in this process, the extent and nature of nuclear DNA fragmentation after NB dosing were assessed using both terminal deoxynucleotidyl transferase-mediated dUTP nick end-labeling (TUNEL) and DNA gel electrophoresis, in… (More)
DOI: 10.1007/s002040050505

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