Involvement of an NAD(P)H oxidase-like enzyme in superoxide anion and hydrogen peroxide generation by rat type II cells.

@article{Klaveren1997InvolvementOA,
  title={Involvement of an NAD(P)H oxidase-like enzyme in superoxide anion and hydrogen peroxide generation by rat type II cells.},
  author={Rob J. van Klaveren and Chris Roelant and M. A. Boogaerts and Maurits M Demedts and Benoit Nemery},
  journal={Thorax},
  year={1997},
  volume={52 5},
  pages={465-71}
}
BACKGROUND Although alveolar macrophages are considered to be the primary cellular mediators of host defence in the lung, there is increasing evidence that type II cells may also play an active role in host defence. A study was undertaken to investigate whether type II cells generate O2-. and H2O2 via an NADPH oxidase-like system and whether exposure of the… CONTINUE READING