Involvement of alpha-adrenoceptors in para-hydroxyamphetamine-induced head-twitch response

@article{Tadano1987InvolvementOA,
  title={Involvement of alpha-adrenoceptors in para-hydroxyamphetamine-induced head-twitch response},
  author={T. Tadano and S. Satoh and K. Kisara and Y. Arai and H. Kinemuchi},
  journal={Neuropharmacology},
  year={1987},
  volume={26},
  pages={1463-1467}
}
The effect of some drugs with a higher selectivity for either the alpha 1- or alpha 2-adrenoceptors on the head-twitches induced by intracerebroventricular administration of p-hydroxyamphetamine (p-OHA) in mice, have been studied. Pretreatment with yohimbine increased the number of head-twitches induced by p-OHA, whereas pretreatment with clonidine or prazosin reduced the number of responses. The decrease in head-twitches produced by clonidine was completely antagonized by pretreatment with… Expand

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