Involvement of alpha 2-adrenoreceptors and G proteins in the modulation of platelet secretion in response to Streptococcus sanguis.

@article{Herzberg1993InvolvementOA,
  title={Involvement of alpha 2-adrenoreceptors and G proteins in the modulation of platelet secretion in response to Streptococcus sanguis.},
  author={Mark C. Herzberg and Lissy Kalliyana Krishnan and G. D. Macfarlane},
  journal={Critical reviews in oral biology and medicine : an official publication of the American Association of Oral Biologists},
  year={1993},
  volume={4 3-4},
  pages={435-42}
}
In the presence of plasma, human platelets secrete the contents of their dense granules and then aggregate in response to certain strains of Streptococcus sanguis. After 2 to 5 min of incubation with streptococci, platelets from fast-responding donors will begin to aggregate. Slow responders aggregate after a longer delay. Platelets may secrete after a short (fast responder) or long (slow responder) delay because of differences in the basal levels or responses to potentiating catecholamines. To… CONTINUE READING