Involvement of adiponectin in the pathogenesis of dystrophinopathy

  title={Involvement of adiponectin in the pathogenesis of dystrophinopathy},
  author={Michel Abou-Samra and Sophie Lecompte and Olivier Schakman and Laurence Noel and Marie C. Many and Philippe Gailly and Sonia M. Brichard},
  booktitle={Skeletal Muscle},
The hormone adiponectin (ApN) is decreased in the metabolic syndrome, where it plays a key pathogenic role. ApN also exerts some anti-inflammatory effects on skeletal muscles in mice exposed to acute or chronic inflammation. Here, we investigate whether ApN could be sufficiently potent to counteract a severe degenerative muscle disease, with an inflammatory component such as Duchenne muscular dystrophy (DMD). Mdx mice (a DMD model caused by dystrophin mutation) were crossed with mice… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 5 times over the past 90 days. VIEW TWEETS
7 Citations
48 References
Similar Papers


Publications citing this paper.


Publications referenced by this paper.
Showing 1-10 of 48 references

Similar Papers

Loading similar papers…