• DOI:10.1016/j.brainres.2006.01.038
Corpus ID: 30487517

Involvement of adenosine A2A and dopamine receptors in the locomotor and sensitizing effects of cocaine

@article{Filip2006InvolvementOA,
  title={Involvement of adenosine A2A and dopamine receptors in the locomotor and sensitizing effects of cocaine},
  author={M. Filip and M. Frankowska and M. Zaniewska and E. Przegaliński and K. Fuxe},
  journal={Brain Research},
  year={2006},
  volume={1077},
  pages={67-80}
}

M. Filip, M. Frankowska, +2 authors K. Fuxe

Published 2006

Chemistry, Medicine

Brain Research

Recent data indicate that cocaine locomotor responses may be influenced by dopamine (DA) neurotransmission and adenosine neuromodulation involving the A2A receptor (A2AR). Male Wistar rats were injected with MSX-3 (1-25 mg/kg; an antagonist of A2AR), CGS 21680 (0.05-0.2 mg/kg; an agonist of A2AR), SCH 23390 (0.125-0.25 mg/kg; an antagonist of DA D1/5R), raclopride (0.1-0.8 mg/kg; an antagonist of DA D2/3R), nafadotride (0.2-0.4 mg/kg; an antagonist of DA D3R) or 7-OH-PIPAT (0.01-1 mg/kg; an… CONTINUE READING

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