Involvement of ack-pta operon products in alpha-ketobutyrate metabolism by Salmonella typhimurium.

@article{Dyk1987InvolvementOA,
  title={Involvement of ack-pta operon products in alpha-ketobutyrate metabolism by Salmonella typhimurium.},
  author={Tina K Van Dyk and Robert A Larossa},
  journal={Molecular & general genetics : MGG},
  year={1987},
  volume={207 2-3},
  pages={435-40}
}
The herbicide sulfometuron methyl inhibits acetolactate synthase II of Salmonella typhimurium, resulting in toxic accumulation of alpha-ketobutyrate. Four mutants, containing Tn10 insertions in the acetate kinase (ack) or phosphotransacetylase (pta) genes, were found among a collection of mutants hypersensitive to sulfometuron methyl. The genetic map location of these four Tn10 insertions at 46 min was identical to that of ack and pta point mutants. The insertion and point mutants shared the… CONTINUE READING
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