Involvement of a polymorphism in the 5-HT2A receptor gene in impulsive behavior

  title={Involvement of a polymorphism in the 5-HT2A receptor gene in impulsive behavior},
  author={M. Nomura and I. Kusumi and M. Kaneko and T. Masui and M. Daiguji and T. Ueno and T. Koyama and Y. Nomura},
  • M. Nomura, I. Kusumi, +5 authors Y. Nomura
  • Published 2006
  • Psychology, Medicine
  • Psychopharmacology
  • Rationale and objectiveImpulsive behavior has been suggested to occur due to a dysfunction of serotonergic 5-HT neurotransmission. After evaluation by a self-reporting measure, a polymorphism in the promoter of the 5-HT2A receptor gene has been proposed to underlie the impulsive behavior; however, this hypothesis is not convincing. In this study, we examined whether this 5-HT2A receptor gene polymorphism is involved in impulsive aggression by evaluating a behavioral task (go/no-go task) in… CONTINUE READING
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