Involvement of TSC genes and differential expression of other members of the mTOR signaling pathway in oral squamous cell carcinoma

@article{Chakraborty2008InvolvementOT,
  title={Involvement of TSC genes and differential expression of other members of the mTOR signaling pathway in oral squamous cell carcinoma},
  author={Sanjukta Chakraborty and S. M. Azeem Mohiyuddin and K S Gopinath and Arun Kumar},
  journal={BMC Cancer},
  year={2008},
  volume={8},
  pages={163 - 163}
}
Despite extensive research, the five-year survival rate of oral squamous cell carcinoma (OSCC) patients has not improved. Effective treatment of OSCC requires the identification of molecular targets and signaling pathways to design appropriate therapeutic strategies. Several genes from the mTOR signaling pathway are known to be dysregulated in a wide spectrum of cancers. However, not much is known about the involvement of this pathway in tumorigenesis of OSCC. We therefore investigated the role… CONTINUE READING