Involvement of SSAO-mediated deamination in adipose glucose transport and weight gain in obese diabetic KKAy mice.

@article{Yu2004InvolvementOS,
  title={Involvement of SSAO-mediated deamination in adipose glucose transport and weight gain in obese diabetic KKAy mice.},
  author={Peter H.F. Yu and Michael Chuansan Wang and Hui Fan and Yulin Deng and Diana Gubisne-Haberle},
  journal={American journal of physiology. Endocrinology and metabolism},
  year={2004},
  volume={286 4},
  pages={E634-41}
}
Semicarbazide-sensitive amine oxidase (SSAO) is located on outer surfaces of adipocytes and endothelial and vascular smooth muscle cells. This enzyme catalyzes deamination of methylamine and aminoacetone, leading to production of toxic formaldehyde and methylglyoxal, respectively, as well as hydrogen peroxide and ammonium. Several lines of evidence suggest… CONTINUE READING