Involvement of RhoGDI2 in the resistance of colon cancer cells to 5-fluorouracil.

@article{Zheng2010InvolvementOR,
  title={Involvement of RhoGDI2 in the resistance of colon cancer cells to 5-fluorouracil.},
  author={Zhong A. Zheng and Jianfang Li and Xiangyi He and Xuehua Chen and Beiqin Yu and Jun Young Ji and Jianian Zhang and Tingfeng Wang and Qin-long Gu and Zheng-gang Zhu and Bing-Ya Liu},
  journal={Hepato-gastroenterology},
  year={2010},
  volume={57 102-103},
  pages={1106-12}
}
BACKGROUND/AIMS The acquisition of resistance to 5-FU is one of the most prominent obstacles to successful chemotherapy, and the mechanisms underlying the resistance are not fully understood. The aim of this study is to identify novel mediators of 5-FU resistance in colon cancer cells. METHODOLOGY LoVo colon cancer cells were induced to 5-FU resistance in… CONTINUE READING