Involvement of RORγt-overexpressing T cells in the development of autoimmune arthritis in mice

@inproceedings{Kondo2015InvolvementOR,
  title={Involvement of RORγt-overexpressing T cells in the development of autoimmune arthritis in mice},
  author={Yuya Kondo and Zhaojin Yao and Masahiro Tahara and Mana Iizuka and Masahiro Yokosawa and Shunta Kaneko and Seiji Segawa and Hiroto Tsuboi and Keigyou Yoh and Satoru Takahashi and Isao Matsumoto and Takayuki Sumida},
  booktitle={Arthritis research & therapy},
  year={2015}
}
INTRODUCTION Differentiation of T helper 17 cells is dependent on the expression of transcription retinoid-related orphan receptor gamma t (RORγt). The purpose of our study is to determine the role of RORγt expression in T cells on the development of collagen-induced arthritis (CIA). METHODS CIA was induced in C57BL/6 and T cell-specific RORγt transgenic (RORγt Tg) mice. At day 10 post-1st-immunization, lymph node (LN) cells were cultured with type II collagen (CII), and the expression levels… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 6 times over the past 90 days. VIEW TWEETS
3 Citations
36 References
Similar Papers

References

Publications referenced by this paper.
Showing 1-10 of 36 references

Similar Papers

Loading similar papers…