Involvement of Opioid System, TRPM8, and ASIC Receptors in Antinociceptive Effect of Arrabidaea brachypoda (DC) Bureau

@article{Rodrigues2017InvolvementOO,
  title={Involvement of Opioid System, TRPM8, and ASIC Receptors in Antinociceptive Effect of Arrabidaea brachypoda (DC) Bureau},
  author={Vinicius P Rodrigues and C. Q. Rocha and L. L. P{\'e}rico and R. C. Santos and Rie Ohara and C. M. Nishijima and E. Ferreira Queiroz and J. Wolfender and L. R. Rocha and A. R. Santos and W. Vilegas and C. Hiruma-Lima},
  journal={International Journal of Molecular Sciences},
  year={2017},
  volume={18}
}
Arrabidaea brachypoda (DC) Bureau is a medicinal plant found in Brazil. Known as “cipó-una”, it is popularly used as a natural therapeutic agent against pain and inflammation. This study evaluated the chemical composition and antinociceptive activity of the dichloromethane fraction from the roots of A. brachypoda (DEAB) and its mechanism of action. The chemical composition was characterized by high-performance liquid chromatography, and this fraction is composed only of dimeric flavonoids. The… Expand
Endogenous opiates and behavior: 2017
Characterization of the in vitro cytotoxic effects of brachydins isolated from Fridericia platyphylla in a prostate cancer cell line
Bioactive Phenolics and Polyphenols: Current Advances and Future Trends

References

SHOWING 1-10 OF 58 REFERENCES
Anti-inflammatory and antinociceptive effects of Arrabidaea brachypoda (DC.) Bureau roots.
Potent antinociceptive effects of TRK-820, a novel κ-opioid receptor agonist
Antinociception of β-D-glucan from Pleurotus pulmonarius is possibly related to protein kinase C inhibition.
4-Hydroxynonenal, an endogenous aldehyde, causes pain and neurogenic inflammation through activation of the irritant receptor TRPA1
TRPM8 is the principal mediator of menthol-induced analgesia of acute and inflammatory pain
A CLASSIFICATION OF OPIATE RECEPTORS THAT MEDIATE ANTINOCICEPTION IN ANIMALS
  • M. Tyers
  • Chemistry, Medicine
  • British journal of pharmacology
  • 1980
Dimeric flavonoids from Arrabidaea brachypoda and assessment of their anti-Trypanosoma cruzi activity.
The capsaicin test in mice for evaluating tachykinin antagonists in the spinal cord
...
1
2
3
4
5
...