Involvement of Opioid System, TRPM8, and ASIC Receptors in Antinociceptive Effect of Arrabidaea brachypoda (DC) Bureau

@inproceedings{Rodrigues2017InvolvementOO,
  title={Involvement of Opioid System, TRPM8, and ASIC Receptors in Antinociceptive Effect of Arrabidaea brachypoda (DC) Bureau},
  author={Vin{\'i}cius Peixoto Rodrigues and Cl{\'a}udia Quintino da Rocha and Larissa Lucena P{\'e}rico and Raquel C{\'a}ssia Santos and Rie Ohara and Catarine Massucato Nishijima and Emerson Ferreira Queiroz and Jean-Luc Wolfender and L{\'u}cia Regina Machado Rocha and Adair R Santos and Wagner Vilegas and Cl{\'e}lia Akiko Hiruma-Lima},
  booktitle={International journal of molecular sciences},
  year={2017}
}
Arrabidaea brachypoda (DC) Bureau is a medicinal plant found in Brazil. Known as "cipó-una", it is popularly used as a natural therapeutic agent against pain and inflammation. This study evaluated the chemical composition and antinociceptive activity of the dichloromethane fraction from the roots of A. brachypoda (DEAB) and its mechanism of action. The chemical composition was characterized by high-performance liquid chromatography, and this fraction is composed only of dimeric flavonoids. The… CONTINUE READING

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