Involvement of NO generation in aluminum-induced cell death.

@article{Satoh2007InvolvementON,
  title={Involvement of NO generation in aluminum-induced cell death.},
  author={Eiko Satoh and Iho Yasuda and Tomoko Yamada and Yasuyuki Suzuki and Takao Ohyashiki},
  journal={Biological \& pharmaceutical bulletin},
  year={2007},
  volume={30 8},
  pages={
          1390-4
        }
}
Previously, we have reported that the exposure of PC12 cells to the aluminum-maltolate complex (Al(maltol)(3)) results in decreased cell viability via the apoptotic cell death pathway. In this study, we have used several nitric oxide synthase (NOS) inhibitors and the NO generator diethylenetriamine NONOate (DETA NONOate) to examine whether or not intracellular nitric oxide (NO) generation is involved in the onset mechanism of Al(maltol)(3)-induced cell death. Cell viability was assessed by… 
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