Involvement of NF-κBIZ and related cytokines in age-associated renal fibrosis

Abstract

Chronic inflammation is a major contributor to age-related nephropathic changes, including renal fibrosis. In this study, various experimental paradigms were designed to delineate the role played by NF-κBIZ (also known as IκBζ) in age-associated renal fibrosis. Analyses based on RNA-sequencing findings obtained by next generation sequencing (NGS) revealed… (More)
DOI: 10.18632/oncotarget.14614

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