Involvement of MAPK proteins in bystander effects induced by chemicals and ionizing radiation.

@article{Asur2010InvolvementOM,
  title={Involvement of MAPK proteins in bystander effects induced by chemicals and ionizing radiation.},
  author={Rajalakshmi S Asur and Mamtha Balasubramaniam and Brian Marples and Robert A. Thomas and James D. Tucker},
  journal={Mutation research},
  year={2010},
  volume={686 1-2},
  pages={15-29}
}
Many studies have examined bystander effects induced by ionizing radiation, however few have evaluated the ability of chemicals to induce similar effects. We previously reported the ability of two chemicals, mitomycin C (MMC) and phleomycin (PHL) to induce bystander effects in normal human lymphoblastoid cell lines. The focus of the current study was to determine the involvement of the MAPK proteins in bystander effects induced by physical and chemical DNA damaging agents and to evaluate the… CONTINUE READING

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