Involvement of L-glutamate and ATP in the neurotransmission of the sympathoexcitatory component of the chemoreflex in the commissural nucleus tractus solitarii of awake rats and in the working heart-brainstem preparation.

@article{Braga2007InvolvementOL,
  title={Involvement of L-glutamate and ATP in the neurotransmission of the sympathoexcitatory component of the chemoreflex in the commissural nucleus tractus solitarii of awake rats and in the working heart-brainstem preparation.},
  author={Valdir de Andrade Braga and Renato N Soriano and Alex L Braccialli and Patr{\'i}cia Maria De Paula and Leni G H Bonagamba and Julian Paton and Benedito H Machado},
  journal={The Journal of physiology},
  year={2007},
  volume={581 Pt 3},
  pages={1129-45}
}
Peripheral chemoreflex activation with potassium cyanide (KCN) in awake rats or in the working heart-brainstem preparation (WHBP) produces: (a) a sympathoexcitatory/pressor response; (b) bradycardia; and (c) an increase in the frequency of breathing. Our main aim was to evaluate neurotransmitters involved in mediating the sympathoexcitatory component of the chemoreflex within the nucleus tractus solitarii (NTS). In previous studies in conscious rats, the reflex bradycardia, but not the pressor… CONTINUE READING

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