Involvement of GLUT-4 in the stimulatory effect of rutin on glucose uptake in rat soleus muscle.

@article{Kappel2013InvolvementOG,
  title={Involvement of GLUT-4 in the stimulatory effect of rutin on glucose uptake in rat soleus muscle.},
  author={Virg{\'i}nia Demarchi Kappel and Luisa H. Cazarolli and Danielle Fontana Pereira and B{\'a}rbara Graziela Postal and Ariane Zamoner and Fl{\'a}vio Henrique Reginatto and F{\'a}tima R. M. B. Silva},
  journal={The Journal of pharmacy and pharmacology},
  year={2013},
  volume={65 8},
  pages={
          1179-86
        }
}
OBJECTIVES The aim of this study was to investigate the in-vitro effect of rutin on glucose uptake in an insulin target (soleus muscle) and the mechanism of action involved. METHODS Isolated soleus muscles from rats were treated with rutin (500 μm) with or without the following inhibitors; hydroxy-2-naphthalenylmethylphosphonic acid trisacetoxymethyl ester (HNMPA(AM)3 ), an insulin receptor tyrosine kinase activity inhibitor, wortmannin, an inhibitor of phosphatidylinositol 3-kinase (PI3K… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 13 CITATIONS

References

Publications referenced by this paper.
SHOWING 1-10 OF 37 REFERENCES

Participation of protein kinases in the stimulant action of GLP-1 on 2-deoxy-D-glucose uptake by normal rat skeletal muscle.

  • Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme
  • 2005
VIEW 5 EXCERPTS
HIGHLY INFLUENTIAL

MEK inhibitors impair insulin-stimulated glucose uptake in 3T3-L1 adipocytes.

  • American journal of physiology. Endocrinology and metabolism
  • 2004
VIEW 6 EXCERPTS
HIGHLY INFLUENTIAL

Cleavage of structural proteins during

VIEW 2 EXCERPTS
HIGHLY INFLUENTIAL

Diag - nosis and classification of Diabetes mellitus

RA DeFronzo
  • Diabetes Care
  • 2011

Effects of flavonoids on a-glucosidase activity: potential targets for glucose homeostasis

DF Pereira
  • Nutrition
  • 2011
VIEW 2 EXCERPTS