Involvement of Fc epsilon RII/CD23 and L-arginine-dependent pathway in IgE-mediated stimulation of human monocyte functions.

@article{Mossalayi1994InvolvementOF,
  title={Involvement of Fc epsilon RII/CD23 and L-arginine-dependent pathway in IgE-mediated stimulation of human monocyte functions.},
  author={Mohammad Djavad Mossalayi and N. Paul-Eugene and F Ouaaz and Michel Arock and J. P. Kolb and E Kilchherr and Patrice Debr{\'e} and Bernard Dugas},
  journal={International immunology},
  year={1994},
  volume={6 7},
  pages={931-4}
}
Elevated IgE levels are commonly observed during the inflammatory responses in allergy and a variety of infections. This Ig activates the release of multiple mediators from monocytes/macrophages. In the present work, we attempted to clarify the IgE-dependent events involved in the activation of monocyte functions. IgE-anti-IgE immune complexes induce the production of tumor necrosis factor-alpha, oxygen radicals, IL-6 and thromboxane B2 from normal human purified monocytes. Expression and cross… CONTINUE READING

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