Involvement of Endoplasmic Reticulum Stress-Mediated C/EBP Homologous Protein Activation in Coxsackievirus B3-Induced Acute Viral Myocarditis.

@article{Cai2015InvolvementOE,
  title={Involvement of Endoplasmic Reticulum Stress-Mediated C/EBP Homologous Protein Activation in Coxsackievirus B3-Induced Acute Viral Myocarditis.},
  author={Zhejun Cai and Li Shen and Hong Ma and Jin Yang and Du Yang and Han Chen and Jia Wei and Qiulun Lu and Dao Wen Wang and Meixiang Xiang and Jian'an Wang},
  journal={Circulation. Heart failure},
  year={2015},
  volume={8 4},
  pages={809-18}
}
BACKGROUND This study tested the hypothesis whether endoplasmic reticulum (ER) stress/C/EBP homologous protein (CHOP) signaling is linked with coxsackievirus B3 (CVB3)-induced acute viral myocarditis (AVMC) in vivo. METHODS AND RESULTS AVMC was induced by intraperitoneal injection of 1000 tissue culture infectious dose (TCID50) of CVB3 virus in mice. In… CONTINUE READING