Involvement of Endogeneous Glutamate in the Stimulatory Effect of Norepinephrine and Serotonin on the Hypothalamo-Pituitary-Adrenocortical Axis

@article{Feldman2004InvolvementOE,
  title={Involvement of Endogeneous Glutamate in the Stimulatory Effect of Norepinephrine and Serotonin on the Hypothalamo-Pituitary-Adrenocortical Axis},
  author={Shaul Feldman and Joseph Weidenfeld},
  journal={Neuroendocrinology},
  year={2004},
  volume={79},
  pages={43 - 53}
}
The effects of ionotropic glutamate receptor antagonists on the pituitary adrenal responses following injections of norepinephrine (NE) and serotonin (5-HT) receptor agonists into the hypothalamic paraventricular nucleus (PVN) or electrical stimulation of central NE and 5-HT pathways were studied in anesthetized male rats. PVN injections of an α1-adrenergic receptor agonist or a serotonergic 5-HT1A receptor agonist markedly increased both adrenocorticotropin (ACTH) and corticosterone (CS) serum… Expand
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