Involvement of CaV3.1 T-type calcium channels in cell proliferation in mouse preadipocytes.

  title={Involvement of CaV3.1 T-type calcium channels in cell proliferation in mouse preadipocytes.},
  author={Atsushi Oguri and Tomofumi Tanaka and Haruko Iida and Kentarou Meguro and Haruhito Takano and Hitoshi Oonuma and Satoshi Nishimura and Toshihiro Morita and Tatsuya Yamasoba and Ryozo Nagai and Toshiaki Nakajima},
  journal={American journal of physiology. Cell physiology},
  volume={298 6},
Voltage-gated Ca(2+) channels (Ca(V)) are ubiquitously expressed in various cell types and play vital roles in regulation of cellular functions including proliferation. However, the molecular identities and function of Ca(V) remained unexplored in preadipocytes. Therefore, whole cell voltage-clamp technique, conventional/quantitative real-time RT-PCR, Western blot, small interfering RNA (siRNA) experiments, and immunohistochemical analysis were applied in mouse primary cultured preadipocytes as… CONTINUE READING


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