Involvement of CC chemokine ligand 18 (CCL18) in normal and pathological processes.

  title={Involvement of CC chemokine ligand 18 (CCL18) in normal and pathological processes.},
  author={Evemie Schutyser and Ann Richmond and Jo Van Damme},
  journal={Journal of leukocyte biology},
  volume={78 1},
CC chemokine ligand 18 (CCL18) was originally discovered as pulmonary and activation-regulated chemokine (PARC), dendritic cell (DC)-chemokine 1 (DC-CK1), alternative macrophage activation-associated CC chemokine-1 (AMAC-1), and macrophage inflammatory protein-4 (MIP-4). CCL18 primarily targets lymphocytes and immature DC, although its agonistic receptor remains unknown so far. CCL18 is mainly expressed by a broad range of monocytes/macrophages and DC. A more profound understanding of the… CONTINUE READING


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