Involvement of Arabidopsis HOS15 in histone deacetylation and cold tolerance.

  title={Involvement of Arabidopsis HOS15 in histone deacetylation and cold tolerance.},
  author={Jianhua Zhu and Jae cheol Jeong and Yanmei Zhu and Irina Sokolchik and Saori Miyazaki and Jian-Kang Zhu and Paul Mike Hasegawa and Hans J. Bohnert and Huazhong Shi and Dae-Jin Yun and Ray Anthony Bressan},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  volume={105 12},
Histone modification in chromatin is one of the key control points in gene regulation in eukaryotic cells. Protein complexes composed of histone acetyltransferase or deacetylase, WD40 repeat protein, and many other components have been implicated in this process. Here, we report the identification and functional characterization of HOS15, a WD40-repeat protein crucial for repression of genes associated with abiotic stress tolerance through histone deacetylation in Arabidopsis. HOS15 shares high… CONTINUE READING


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