Involvement of ATP-sensitive K+ channels in the sustained coronary vasodilator response to adenosine in dogs.

@article{Orito1993InvolvementOA,
  title={Involvement of ATP-sensitive K+ channels in the sustained coronary vasodilator response to adenosine in dogs.},
  author={Kensuke Orito and Keisuke Satoh and Norio Taira},
  journal={European journal of pharmacology},
  year={1993},
  volume={231 2},
  pages={183-9}
}
Coronary vasodilator mechanisms of adenosine were investigated in isolated canine papillary muscle preparations cross-circulated through the anterior septal artery with support dogs. Infusions of adenosine (1-3000 nmol/min) for 3 min into this artery caused a transient increase (the initial phase) in blood flow followed by a sustained increase (the… CONTINUE READING