Involvement of 5HT3 Receptors in Anti-Inflammatory Effects of Tropisetron on Experimental TNBS-Induced Colitis in Rat.

@article{Motavallian2013InvolvementO5,
  title={Involvement of 5HT3 Receptors in Anti-Inflammatory Effects of Tropisetron on Experimental TNBS-Induced Colitis in Rat.},
  author={Azadeh Motavallian and Mohsen Minaiyan and Mohammad Rabbani and Sasan Andalib and Parvin Mahzouni},
  journal={BioImpacts : BI},
  year={2013},
  volume={3 4},
  pages={
          169-76
        }
}
  • Azadeh Motavallian, Mohsen Minaiyan, +2 authors Parvin Mahzouni
  • Published in BioImpacts : BI 2013
  • Medicine
  • INTRODUCTION There is a pressing need for research leading to the development of new effective drugs with lower side effects and more efficacy for treating inflammatory bowel disease (IBD). The analgesic and anti-inflammatory properties of 5-Hydroxytryptamine (5-HT)-3 receptor antagonists have been shown in in vivo and in vitro studies. The present study was designed to investigate the effects of tropisetron, a 5-HT3 receptor antagonist, on an immune-based animal model of IBD. METHODS In the… CONTINUE READING

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