Involvement of 5-HT1B receptors within the ventral tegmental area in regulation of mesolimbic dopaminergic neuronal activity via GABA mechanisms: a study with dual-probe microdialysis
@article{Yan2004InvolvementO5, title={Involvement of 5-HT1B receptors within the ventral tegmental area in regulation of mesolimbic dopaminergic neuronal activity via GABA mechanisms: a study with dual-probe microdialysis}, author={Qing-shan Yan and Shi-Zhong Zheng and Shu-E Yan}, journal={Brain Research}, year={2004}, volume={1021}, pages={82-91} }
72 Citations
Ethanol and Mesolimbic Serotonin / Dopamine Interactions via 5-HT-lB Receptors
- Biology, Chemistry
The results suggest that activation of VTA 5-HTIB receptors increases mesolimbic DA neuron activities, and this increased DA neuron activity may be associated, at least in part, with the 5HTIB receptor-mediated inhibition of Vta GABA release.
Involvement of 5-HT1B receptors within the ventral tegmental area in ethanol-induced increases in mesolimbic dopaminergic transmission
- Biology, MedicineBrain Research
- 2005
Award Number: DAMD17-02-1-0187 TITLE: Ethanol and Mesolimbic Serotonin/Dopamine Interactions via 5HT-1B Receptors
- Biology, Chemistry
- 2007
The results suggest that activation of VTA 5-HT1B receptors increases mesolimbic DA neuron activities, and this increased DA neuron activity may be associated, at least in part, with the 5 HT1B receptor-mediated inhibition of Vta GABA release.
TITLE: Ethanol and Mesolimbic Serotonin/Dopamine Interactions Via 5-HT1B Receptors
- Biology, Medicine
- 2006
The results suggest that blockade and activation of VTA 5-HT1B receptors attenuates and potentiates the neurochemical effects of ethanol, respectively, and support the suggestion that VTA 4-HT2B receptors may be involved in part in mediating the activating effects ofanol on mesolimbic DA neurons.
Dual Effect of 5-HT1B/1D Receptors on Dopamine Neurons in Ventral Tegmental Area: Implication for the Functional Switch After Chronic Cocaine Exposure
- Biology, MedicineBiological Psychiatry
- 2020
Peripheral Administration of Ethanol Results in a Correlated Increase in Dopamine and Serotonin Within the Posterior Ventral Tegmental Area.
- MedicineAlcohol and alcoholism
- 2016
The current findings suggest that the ability of EtOH to stimulate DA activity within the mesolimbic system may be modulated by increases in 5-HT release within the pVTA.
Effects of systemic 5-HT(1B) receptor compounds on ventral tegmental area intracranial self-stimulation thresholds in rats.
- Biology, PsychologyEuropean journal of pharmacology
- 2009
Serotonin control of central dopaminergic function: focus on in vivo microdialysis studies.
- Biology, PsychologyProgress in brain research
- 2008
Neural Circuits Associated with 5-HT1B Receptor Agonist Inhibition of Methamphetamine Seeking in the Conditioned Place Preference Model.
- Biology, PsychologyACS chemical neuroscience
- 2019
The findings suggest that CP94253 attenuates the motivational effects of the Meth-associated environment and highlight the amygdala, VTA, NAc, and dorsomedial striatum as potential regions involved in this effect.
Serotonin1B heteroreceptor activation induces an antidepressant-like effect in mice with an alteration of the serotonergic system.
- Biology, PsychologyJournal of psychiatry & neuroscience : JPN
- 2008
The results demonstrate that the antidepressant-like effect of SSRIs in the FST requires the activation of 5-HT1B heteroreceptors, which antagonizes the effect of selective serotonin reuptake inhibitors (SSRIs).
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