• DOI:10.1016/0091-3057(94)00421-E
Corpus ID: 32099533

Involvement of 5-HT1A receptors in the anxiolytic action of S 14671 in the pigeon conflict test

@article{Schreiber1995InvolvementO5,
  title={Involvement of 5-HT1A receptors in the anxiolytic action of S 14671 in the pigeon conflict test},
  author={R. Schreiber and M. Brocco and B. D. Ladonchamps and M. Millan},
  journal={Pharmacology Biochemistry and Behavior},
  year={1995},
  volume={51},
  pages={211-215}
}

R. Schreiber, M. Brocco, +1 author M. Millan

Published 1995

Chemistry, Medicine

Pharmacology Biochemistry and Behavior

In the pigeon conflict test of anxiety, the novel, high efficacy 5-HT1A receptor ligand, S 14671, very potently [minimal effective dose (MED): 0.0025 mg/kg, IM] and markedly (maximal percentage increase relative to control: 17232%) increased punished responding. In analogy, its structural analogue, the 5-HT1A receptor agonist, S 14506, equipotently, though less markedly, augmented punished responding (MED: 0.0025 mg/kg; maximal effect: 5557%). In contrast, the arylpiperazine 5-HT1A receptor… CONTINUE READING

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