Involvement of 5-HT1A receptors in the anxiolytic action of S 14671 in the pigeon conflict test

@article{Schreiber1995InvolvementO5,
  title={Involvement of 5-HT1A receptors in the anxiolytic action of S 14671 in the pigeon conflict test},
  author={R. Schreiber and M. Brocco and B. D. Ladonchamps and M. Millan},
  journal={Pharmacology Biochemistry and Behavior},
  year={1995},
  volume={51},
  pages={211-215}
}
  • R. Schreiber, M. Brocco, +1 author M. Millan
  • Published 1995
  • Chemistry, Medicine
  • Pharmacology Biochemistry and Behavior
  • In the pigeon conflict test of anxiety, the novel, high efficacy 5-HT1A receptor ligand, S 14671, very potently [minimal effective dose (MED): 0.0025 mg/kg, IM] and markedly (maximal percentage increase relative to control: 17232%) increased punished responding. In analogy, its structural analogue, the 5-HT1A receptor agonist, S 14506, equipotently, though less markedly, augmented punished responding (MED: 0.0025 mg/kg; maximal effect: 5557%). In contrast, the arylpiperazine 5-HT1A receptor… CONTINUE READING
    13 Citations
    S 15535, a novel benzodioxopiperazine ligand of serotonin (5-HT)1A receptors: II. Modulation of hippocampal serotonin release in relation to potential anxiolytic properties.
    • 72
    • PDF
    Evidence for the involvement of the monoaminergic system in the antidepressant-like effect of magnesium
    • 87
    Discriminative stimulus effects of 8-hydroxy-2-(di-n-propylamino)tetralin in pigeons and rats: species similarities and differences.
    • M. Kleven, W. Koek
    • Chemistry, Medicine
    • The Journal of pharmacology and experimental therapeutics
    • 1998
    • 20
    Anxiolytic-like actions of buspirone in a runway model of intravenous cocaine self-administration
    • 28
    Structure-activity relationships of serotonin 5-HT7 receptors ligands: A review.
    • 3

    References

    SHOWING 1-10 OF 24 REFERENCES
    Anticonflict effects of the 5-HT1A compound flesinoxan
    • 30
    Behavioral studies with anxiolytic drugs. V. Behavioral and in vivo neurochemical analyses in pigeons of drugs that increase punished responding.
    • 64