Involvement of 3D osteoblast migration and bone apatite during in vitro early osteocytogenesis.


The transition from osteoblast to osteocyte is described to occur through passive entrapment mechanism (self-buried, or embedded by neighboring cells). Here, we provide evidence of a new pathway where osteoblasts are "more" active than generally assumed. We demonstrate that osteoblasts possess the ability to migrate and differentiate into early osteocytes… (More)
DOI: 10.1016/j.bone.2016.04.031


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