Involvement of β-adrenergic receptors in protein synthesis-dependent late long-term potentiation (LTP) in the dentate gyrus of freely moving rats: the critical role of the LTP induction strength

@article{Straube2003InvolvementO,
  title={Involvement of $\beta$-adrenergic receptors in protein synthesis-dependent late long-term potentiation (LTP) in the dentate gyrus of freely moving rats: the critical role of the LTP induction strength},
  author={Thomas Straube and Julietta U. Frey},
  journal={Neuroscience},
  year={2003},
  volume={119},
  pages={473-479}
}
We have investigated the requirement of beta-adrenergic receptor activation and protein synthesis for the induction and specifically for the maintenance of long-term potentiation (LTP) in the dentate gyrus of freely moving rats in dependency on different LTP-induction procedures. Three tetanization paradigms were used: a relatively weak protocol A (10 bursts of 15 biphasic pulses at 200 Hz; 10-s interburst interval; 0.2-ms pulse width per phase), a stronger protocol B (as protocol A but 20… Expand
Requirement of β‐adrenergic receptor activation and protein synthesis for LTP‐reinforcement by novelty in rat dentate gyrus
Long‐term potentiation (LTP) is supposed to be a cellular mechanism involved in memory formation. Similar to distinct types of memory formation, LTP can be separated into a proteinExpand
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In vitro field potential recordings show that rapid effects of corticosterone do not influence LTP induced by mild tetanization in the hippocampal dentate gyrus, unless GABA(A) receptors are blocked, whereas the beta-adrenergic agonist isoproterenol does initiate a slow-onset, limited amount of potentiation. Expand
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TLDR
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Effect of LTP-reinforcing paradigms on neurotransmitter release in the dentate gyrus of young and aged rats.
TLDR
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