Involution of the rat thymus in experimentally induced hypothyroidism


The thymus, as part of the immune-neuroendocrine axis, is greatly influenced by factors from most endocrine glands, especially the thyroid. Antithyroid drugs (carbimazole and methimazole) were used to induce hypothyroidism in rats. Histological and ultrastructural examination of the thymus showed progressive thymic involution after 4 weeks of drug treatment… (More)
DOI: 10.1007/BF00300217


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@article{AbouRabia1994InvolutionOT, title={Involution of the rat thymus in experimentally induced hypothyroidism}, author={N. Abou-Rabia and Marion D. Kendall}, journal={Cell and Tissue Research}, year={1994}, volume={277}, pages={447-455} }