Invited review: Bacterial lipopolysaccharides and innate immunity

  title={Invited review: Bacterial lipopolysaccharides and innate immunity},
  author={C. Alexander and E. Rietschel},
  journal={Journal of Endotoxin Research},
  pages={167 - 202}
  • C. Alexander, E. Rietschel
  • Published 2001
  • Biology
  • Journal of Endotoxin Research
  • Bacterial lipopolysaccharides (LPS) are the major outer surface membrane components present in almost all Gram-negative bacteria and act as extremely strong stimulators of innate or natural immunity in diverse eukaryotic species ranging from insects to humans. LPS consist of a poly- or oligosaccharide region that is anchored in the outer bacterial membrane by a specific carbohydrate lipid moiety termed lipid A. The lipid A component is the primary immunostimulatory centre of LPS. With respect… CONTINUE READING
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