Invited review: Bacterial lipopolysaccharides and innate immunity

  title={Invited review: Bacterial lipopolysaccharides and innate immunity},
  author={Christian Alexander and Ernst Th. Rietschel},
  journal={Journal of Endotoxin Research},
  pages={167 - 202}
Bacterial lipopolysaccharides (LPS) are the major outer surface membrane components present in almost all Gram-negative bacteria and act as extremely strong stimulators of innate or natural immunity in diverse eukaryotic species ranging from insects to humans. LPS consist of a poly- or oligosaccharide region that is anchored in the outer bacterial membrane by a specific carbohydrate lipid moiety termed lipid A. The lipid A component is the primary immunostimulatory centre of LPS. With respect… 

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