Investigations on the structure of solid lipid nanoparticles (SLN) and oil-loaded solid lipid nanoparticles by photon correlation spectroscopy, field-flow fractionation and transmission electron microscopy.

@article{Jores2004InvestigationsOT,
  title={Investigations on the structure of solid lipid nanoparticles (SLN) and oil-loaded solid lipid nanoparticles by photon correlation spectroscopy, field-flow fractionation and transmission electron microscopy.},
  author={Katja Jores and Wolfgang H Mehnert and Markus Drechsler and Heike Bunjes and Christoph Johann and Karsten M{\"a}der},
  journal={Journal of controlled release : official journal of the Controlled Release Society},
  year={2004},
  volume={95 2},
  pages={217-27}
}
Recently, colloidal dispersions made from mixtures of solid and liquid lipids were described to combine controlled release characteristics with higher drug loading capacities than solid lipid nanoparticles (SLN). It has been proposed that these nanostructured lipid carriers (NLC) are composed of oily droplets which solubilize the drug and which are embedded in a solid lipid matrix. The structures of SLN and NLC based on glyceryl behenate and medium chain triglycerides were characterized by… CONTINUE READING

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