Investigations on the secondary structure of polypeptide chains in polyelectrolyte multilayers and their effect on the adhesion and spreading of osteoblasts.

@article{Grohmann2012InvestigationsOT,
  title={Investigations on the secondary structure of polypeptide chains in polyelectrolyte multilayers and their effect on the adhesion and spreading of osteoblasts.},
  author={Steffi Grohmann and Holger Rothe and Klaus Liefeith},
  journal={Biointerphases},
  year={2012},
  volume={7 1-4},
  pages={62}
}
Inspired by the composition of the native extracellular matrix, biomimetic polyelectrolyte multilayers were assembled from polypeptides and the glycosaminoglycan chondroitin sulfate (CS). To investigate whether peptide conformation imposes an effect on the cell biological functions of osteoblasts, the secondary structure was analyzed by in situ infra-red… CONTINUE READING