Investigations on Aberrant Glycosylation of Glycosphingolipids in Colorectal Cancer Tissues Using Liquid Chromatography and Matrix-Assisted Laser Desorption Time-of-Flight Mass Spectrometry (MALDI-TOF-MS)*

@inproceedings{Holst2013InvestigationsOA,
  title={Investigations on Aberrant Glycosylation of Glycosphingolipids in Colorectal Cancer Tissues Using Liquid Chromatography and Matrix-Assisted Laser Desorption Time-of-Flight Mass Spectrometry (MALDI-TOF-MS)*},
  author={Stephanie Holst and Kathrin Stavenhagen and Crina I. A. Balog and Carolien A. M. Koeleman and Liam M. McDonnell and Oleg A Mayboroda and Aswin Verhoeven and Wilma E. Mesker and Rob A. E. M. Tollenaar and Andr{\'e} M. Deelder and Manfred Wuhrer},
  booktitle={Molecular & cellular proteomics : MCP},
  year={2013}
}
Cancer is a leading cause of death and alterations of glycosylation are characteristic features of malignant cells. Colorectal cancer is one of the most common cancers and its exact causes and biology are not yet well understood. Here, we compared glycosylation profiles of colorectal tumor tissues and corresponding control tissues of 13 colorectal cancer patients to contribute to the understanding of this cancer. Using MALDI-TOF(/TOF)-MS and 2-dimensional LC-MS/MS we characterized enzymatically… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 23 CITATIONS

Similar Papers

Loading similar papers…