Investigations of gene-disease associations: costs and benefits of environmental data.

Abstract

Environmental exposure data may improve statistical power in genetic studies when gene-environment interaction is present. However, resources invested in obtaining exposure data could instead be applied to measure disease status and genotype on more subjects. In a cohort-study setting, we consider the tradeoff between measuring only disease status and… (More)
DOI: 10.1097/EDE.0b013e3182944dd5

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